When Gearbox President Tweeted that he would have a big announcement on December 1st, many people began speculating as to what his big reveal would be. Naturally people looked at past franchises that Gearbox has been involved with and assumed that it could be a new entry into the series. As such Skewed and Reviewed spoke with some companies off the record and the results helped eliminate many theories as to what it could be.
i don't trust him, he's a scam artist
Alien: Colonial Marines 2
I swear guys.. this time it will be better :P
B3 reveal, hopefully
Probably Duke Nukem Forever backwards compatibility
I expect a new Brothers in Arms entry, also the Sag-AFTRA website mentions it.